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Reverse Inflammaging Body and Mind Longevity Medicine

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Affiliate Promotion startsApril 4, 2023 

Summit DateApril 25 – May 2, 2023



Meet Your Speakers


Dr. Robert Lufkin
Overview of inflammaging
  • Inflammation: acute vs chronic inflammaging
  • 9 Hallmarks of Aging and Inflammaging
  • Aging as a Chronic Disease
Dr. Stephen Sideroff and Dr. Robert Lufkin
Welcoming session: Mind/Body Approach
  • Determining what's effective and safe
  • The importance of integrating mind and body perspectives
Mark Hyman, MD
Young Forever: the Emerging Sciences of Longevity
  • The Hallmarks of Aging
  • Biological vs. Chronological Age
  • The Root Causes of the Hallmarks of Aging
Dr. Kelly Halderman
The 9 Hallmarks of Aging
  • Pathogensis of inflammaging
  • Selective antioxidants
  • The 9 hallmarks of Aging
Peter Diamandis, MD
The Future of Longevity
  • The longevity mindset
  • The use of technology in promoting longevity
  • The basics are still most important
Robert Lustig
Metabolic Dysfunction
  • Fructose leads to de novo lipogenesis and oxidative stress
  • Fructose alters the gut microbiome leading to inflammation
  • Sugar reduction reverses metabolic syndrome, without changes in calories or weight
Aubrey de Grey, PhD
Rejuvenation biotechnology: how will it address inflammaging?
  • Inflammaging is the maladaptive, misdirected activation of a normally desirable process
  • Indiscriminate dampening of inflammation is therefore a very imperfect a solution
  • The best solution is to remove the inappropriate target: amyloid, oxidised cholesterol, etc
Eric Gordon, MD
Aging is Another Chronic Illness
  • Cell Danger Response as a roadmap to understand chronic inflammation
  • Cell senescenes in relation to Cell Danger Response
  • The mistaken differences between functional illness and pathological illness
Rakesh M. Suri, MD
Longevity and Inflammaging
  • Challenges of our current health model
  • Value of annual precision diagnostics


Dr. Stephen Sideroff
The Power of the Mind in Healing and Longevity
  • Your beliefs are powerful tools for healing
  • Neuroplasticity
  • The importance of self-regulation
Bruce H. Lipton, PhD
The Biology of Belief
  • Environment, not genes, is the primary determiner of your destiny
  • When you embrace life your body produces more telomerase, the telomere protector
  • 1% of disease comes from genes, 90% comes from stress
Joe Dispenza, DC
The healing power of the mind
  • How meditation effects the brain and body
  • A practical formula for transforming one’s life
  • Results of research on biofeedback and other approaches to self-regulation and optimal functioning
Dr. Austin Perlmutter
Neuroinflammation: What it is, how it happens and what to do about it
  • What is neuroinflammation?
  • 5 major lifestyle variables linked to neuroinflammation
  • Interventions to lower neuroinflammation
  • What are microglial cells and why are they so important to this conversation?
Ari Whitten


James Strole
Immortality is in all of us
  • What is significance of the immortal germline? 
  • What is your perspective on the trauma of death and why is it important?
  • The power of togetherness to advance super longevity
Jeffrey Becker, MD
Unlocking the Promise of Brain-Mind-Soul medicine for mental health
  • Psychiatry ceded brain and soul In the name of medication management
  • Mental health needs to address all layers of the human being: Soul, Mind and Brain
  • How mind and mental health impact aging and longevity
  • How ketamine and other psychedelic medicine offers new elevated tools to help with mental disorders
Daniel F. Kelly, MD
The neuroplastic potential of psychedelics and psychedelic-assisted therapy to enhance well being and longevity
  • The paradigm shift with Psychedelic-assisted therapy
  • The evidence for psychedelics as neuroplastigens
  • Results of clinical trials using psychedelics for mental health
Stephen Porges, PhD
Trauma and the Polyvagal Theory
  • What is the Polyvagal Theory?
  • Explain the nervous system process of social engagement and its evolution and role in self-regulation
  • How do deficits in this system cause several mental and physical disorders
  • Discuss the importance of a sense of safety for self-regulation and reducing inflammation
  • What is your “safe and sound” protocol?


Dr. Robert Lufkin
Medical Elements of Inflammaging
  • Inflammaging Drives Chronic Diseases which determine longevity
  • The gut brain axis and longevity
  • Infectious disease, heart disease, Alzheimer’s disease, and mental health
Dr. Andy Manganaro
  • Coming Soon
Tim Peterson, PhD
The Science & Economics Of Infectious Disease And Aging
  • Infectious disease is an underappreciated aspect of longevity
  • Aging is a multi-hit disease (e.g., many pathogens over our lifetime), therefore we need therapies that combat the multiple insults
  • VitaDAO. a new longevity research funding mechanism
Emeran Mayer, MD
The central role of the brain gut microbiome system in longevity
  • The brain, the gut and the immune system form a system that is essential for homeostasis
  • The gut microbiome mediates between dietary and psychosocial influences
  • The central role of the brain gut immune system in health and disease is reflected in the saying “all diseases start in the gut
Joel Kahn, MD, FACC
Inflammation and Heart Disease
  • Inflammation is a root cause of heart disease
  • Inflammation can be reversed with intensive lifestyle measures
  • Heart disease is reversible with intensive lifestyle measures
Kamyar M. Hedayat, MD
Preventing Alzheimer's Dementia with functional lab testing
  • Pre-Alzheimer's dementia can be treated before dementia sets in
  • Functional lab testing can identify the major factors that lead to dementia: inflammation. amyloid plaques and feelings of loneliness
  • For Alzheimer's dementia, the specific supports need to be identified for each person. A one-size fits all will not work
Dale Bredesen, MD
Why Alzheimer's Is Becoming Optional
  • A new model of Alzheimer's disease and a novel approach to treatment
  • The Subtypes of Alzheimer's disease
  • New trial showing improvement in cognition (not just slowing of decline) in 84% of patients with Alzheimer's or pre-Alzheimer's.
Heather Sandison, ND
Reversing Alzheimer's
  • Alzheimer’s diseaase and inflammation
  • Ketogenic nutrition and Alzheimer’s Disease
  • Multi-factorial treatment approaches
Christopher M. Palmer, MD
Brain Energy: The metabolic theory of mental illness
  • Mental disorders are metabolic disorders of the brain
  • Trauma, stress, and adverse childhood events can have a significant impact on mental and metabolic health
  • Metabolic treatments can play a powerful role in the treatment of mental disorders


Dr. Stephen Sideroff
Measurement of Health and Aging
  • New approaches to measuring longevity
  • The role of the microbiome
  • Emerging technologies
Ryan Smith
Recent improvements in DNA Methylation Based aging analysis and measuring biological age
  • What is an epigenetic clock and what is its history?
  • How can epigenetic clocks be helpful in looking at Inflammaging?
  • What is DNA methylation?
Gordan Lauc, PhD
Glycans as biomarkers and functional effectors of ageing and disease
  • What are glycans? 
  • How do they relate to ageing?
  • Can we change our glycans?
Alex Zhavoronkov, PhD
Artificial intelligence and biological clocks
  • Explain the different types of biological clocks
  • How is artificial intelligence aiding in the study of longevity?
  • Describe some breakthroughs in this area
Michael Dubrovsky
Emerging Technology In At-Home Blood Testing
  • Why track biomarkers?
  • What are the typical markers you measure?
  • What is a silicon hotonic biosensor?
Danny Grannick
Good health starts with a healthy mouth: the role of oral health and the oral microbiome
  • Oral inflammatory disease is associated with chronic systemic diseases
  • The oral microbiome dysbiosis leads to disease and ultimately aging as well
  • Steps to improve the oral microbiome


Dr. Robert Lufkin
Fighting inflammaging with lifestyle approaches
  • The most powerful treatments for inflammaging are lifestyle
  • Fasting and fasting mimics improve inflammaging
  • Sugar is a major driver of inflammaging
  • Biological Age vs. Chronological Age
Isaac Eliaz, MD, MS, LAc
The Survival Paradox and Its effect on Inflammaging
  • The survival paradox works via its protein, galectin-3
  • How galectin-3 fuels inflammation, fibrosis, and inflammaging
  • How to address inflammaging upstream at the source
David Perlmutter, MD, FACN
Diet and Inflammaging
  • How Sugar Drives Inflammaging
  • It’s not only the gluten in grain that is a problem
  • Inflammation and Chronic Disease
Joseph Antoun, MD, PhD, MPP
Fasting & Fasting Nutrition For Healthy Aging
  • How fasting impacts metabolism and cells
  • How fasting is a healthy aging and longevity intervention
  • How to incorporate fasting into our lifestyles
Megan Ramos
Intermittent Fasting for Type 2 Diabetes Reversal
  • Type 2 diabetes is a disease of too much insulin and inflammation
  • How insulin resistance can be reversed
  • How to fast in order to reverse type 2 diabetes
Kara Fitzgerald, ND, IFMCP
Biological Age - Younger You
  • 3 reasons why your genes don't dictate your fate
  • 6 foods to eat to lower your biological age
  • Lifestyle changes to make now to reduce your bio age by over three years in a matter of weeks
Lori Shemek, PhD, CNC
Anti-Inflammatory Nutrition Strategies
  • What are the Forms of Inflammation and Its Role in Longevity and Health
  • How Diet Plays a Critical Role in Protection From Chronic Inflammation and Inflammaging
  • What Supplements Help to Protect Against Inflammaging
Tina Woods, MBA
A vision for quantum healthy longevity
  • What is the UK National Innovation Centre for Ageing
  • The blueprint for a 'Healthy Longevity Innovation Mission'
  • How creativity, emotional intelligence, compassion, & altruism affect longevity


Dr. Stephen Sideroff
Use of Supplements to Enhance Health
  • The many approaches to addressing biochemical deficits in the body
  • Keeping toxins out of the boy
Sandra Kaufmann, MD
Seven tenets of cellular ageing and the Kaufmann rating program
  • The seven tenets of cellular aging
  • What role does stress and the mind play in aging?
  • How to make supplement choices
  • How do you create a personalized longevity protocol
Joseph Mercola, DO
Inflammation and Heart Disease
  • Intensive lifestyle measures can reverse heart disease
  • What makes Omega-6 fats so deleterious to mitochondrial health
  • The benefits of sunlight exposure instead of supplements for vitamin D
Catharine Arnston
The healing and energy benefits of algae
  • What are the different nutrient profiles of algae and their healing benefits? 
  • How does algae help support mitochondria health and reduce inflammation?
  • The scientific research supporting algae benefits
Kevin Ellis
The Inflammation, Bone Loss Connection. How To Protect Yourself From Osteoporosis
  • What causes osteoporosis?
  • What is the connection between inflammation and bone loss?
  • What is the connection between gut health and bone health?
  • What are best approaches to prevent or recover from Osteoporosis?
Nathan S. Bryan, PhD
Nitric Oxide: The Longevity Moleculre
  • What is nitric oxide?
  • How is nitric oxide involved in longevity?
  • How nitric oxide regulates mitochondrial function. telomere length and stem cell function
Brian Vaszily
The Little-Known Yet VERY Common Toxins That Harm You the Most
  • The worst source of toxins that even many "health conscious" people are still feeding their bodies daily -- cosmetics and personal care products
  • Women use an average of 12 personal care/cosmetics daily, which contain an average of 168 different chemicals
  • The physical, emotional and mental dangers associated with cosmetic use
Andrew Salisbury
Can you drink coffee for your health?
  • Coffee contains high levels of antioxidants
  • Discussion of research showing reduced risk of heart disease with regular coffee consumption
  • Link between coffee and brain health


Dr. Robert Lufkin
Fighting inflammaging with Technology
  • Metformin and Rapamycin to reduce inflammaging
  • Controlling the autonomic nervous system to reduce aging
  • Pulsed Electromagnetic fields, plasma dilution, and gene therapy
Nir Barzilai, MD
Inflammaging and Longevity
  • Inflammatory proteins are biomarkers for aging
  • Gerothrapeutics can change inflammatory biomarkers
  • Infllamaging is a hallmark of aging that should be targeted
Matt Kaeberlein, PhD
Targeting biological aging with rapamycin
  • Background on mTOR biology and rapamycin mechanism of action
  • Evidence that mTOR inhibition with rapamycin is an effective strategy for increasing lifespan and healthspan
  • Rapamycin for effects on lifespan and healthspan in companion dogs
Sajad Zalsala, MD
Real-world Data of Longevity Focused Therapies
  • Data from patients using therapies such as metformin, LDN, NAD+, and rapamycin
  • Efforts to make longevity as accessible as possible
  • Updates on clinical trials
William Pawluk, MD, MSc
Pulsed Electromagnetic Fields and Longevity
  • What is EMF?
  • The differences when it comes to PEMFs and EMFs?
  • How do PEMFs reduce inflammation?
Irina Conboy, PhD
Reversing biological age with plasma dilution
  • Mechanism of plasma dilution
  • Plasma dilution results in animal studies
  • Clinical plasma dilution findings
JP Errico
The role of the autonomic nervous system and innate immune cells in inflammaging
  • What is the cholinergic anti-inflammatory pathway?
  • The role of the vagus nerve and aging
  • The importance of the macrophage
Elizabeth (Liz) Parrish, MBA
Gene Therapy to Treat Biological Aging
  • Aging is a disease
  • Gene therapy to treat aging
  • CMV gene therapy delivery systems

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Meet Your Summit Hosts


Robert Lufkin, MD

Robert Lufkin, MD has served as Full Professor at both the UCLA David Geffen School of Medicine and the USC Keck School of Medicine. In addition to being a practicing physician, he is author of over 200 peer reviewed scientific papers, 32 book chapters and 14 books that are available in six languages. He studied computer science at Brown University and completed his medical degree at the University of Virginia School of Medicine. His honors include serving as President of the Society of Magnetic Resonance Imaging, President of the American Society of Head and Neck Radiology, and numerous other professional affiliations. Among his many inventions including several patents in artificial intelligence, he developed an MR-compatible biopsy needle which is used worldwide today as the “Lufkin Needle.” He has also founded and/or invested in numerous technology companies.

He is currently a Clinical Professor of Radiology, at the USC Keck School of Medicine with an academic focus on the applied science of longevity. He is also Chief of Metabolic Imaging at a large medical network in southern California. Robert has given invited lectures/keynotes around the world, and was named one of the ‘100 Most Creative People in Los Angeles’ by Buzz Magazine. His latest book “Lies I Taught In Medical School” is in preparation.


Dr. Stephen Sideroff

Dr. Stephen Sideroff is an internationally recognized psychologist, executive and medical consultant and expert in resilience, optimal performance, addiction, neurofeedback, leadership, and mental health.  He has published pioneering research in these fields. He is a professor at UCLA in the Department of Psychiatry & Biobehavioral Sciences and Department of Rheumatology, and director of the Wallenberg Institute of Ethics. He was the founder & former Clinical Director of the Stress Strategies program of UCLA/Santa Monica Hospital and former Clinical Director of Moonview Treatment and Optimal Performance Center. 

His research explores the impact of his model of resilience on longevity. His recent book, “The Path: Mastering the 9 Pillars of Resilience and Success” has been hailed as a true bible for living in balance and spirituality. His new book, “The Resilience Response” will be available in 2023. Participants of Dr. Sideroff’s workshops have said that the experience was “life-changing”.

Dates at a Glance

April 4, 2023

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